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E401 Pill vs Adderall

E401 Pill vs Adderall – comparison


Attention deficit hyperactivity disorder (ADHD) is a neurologically based behavioral condition that affects both children and adults.

In the US, about 9.5% of children between the ages of 3 years and 17 years have been diagnosed with attention deficit hyperactivity disorder.

Here is a comparison of two drugs prescribed for ADHD:

E401 Pill

This orange, round pill is manufactured by Sandoz Pharmaceuticals Inc and contains amphetamine and dextroamphetamine 20 mg.

Amphetamine/dextroamphetamine belongs to a family of drugs known as central nervous system stimulants.

It can help increase your ability to stay focused on an activity, pay attention, and control behavior problems.

Note – this drug is not approved for use by anyone younger than 6 years old.


It contains amphetamine and dextroamphetamine and functions as a central nervous system stimulant for increased attention span, focus, and concentration.

It belongs to a class of compounds called amphetamines.

The Food and Drug Administration originally approved this brand of medication in 1960.

It sits with methamphetamine, cocaine, and heroin, on the Drug Enforcement Administration’s Schedule II list of substances.

Approximately 50 million prescription stimulant drugs are dispensed every year in the United States to treat symptoms of ADHD.

Note – it is not recommended for children under 3 years of age.


E401 Pill

This combination medication is used to treat attention deficit hyperactivity disorder.

In addition, it is used to treat a certain sleeping disorder to help you stay awake during the day.


It may help people with attention deficit hyperactivity disorder to better control their activities and increase their attention spans.

Furthermore, it may prevent symptoms of narcolepsy.

Moreover, the drug can suppress appetite, and many people who want to lose unnecessary weight also abuse this central nervous system stimulant as a diet pill.

About 30% of students had abused an attention deficit hyperactivity disorder stimulant drug at some point as a possible “study enhancer,” according to a study done at the University of Kentucky.

Mechanism of Action

Both drugs work by changing the amounts of certain natural substances in the brain, especially by increasing the levels of norepinephrine, dopamine, and serotonin.

These neurotransmitters form part of the body’s stress response system.

Side Effects

E401 Pill

The most common adverse events include:

  • fast heart rate;
  • loss of appetite;
  • dizziness;
  • stomach pain;
  • sleep problems (insomnia);
  • weight loss;
  • dry mouth;
  • headache;
  • feeling nervous;
  • mood changes.

Serious side effects include:

  • a seizure (convulsions);
  • a feeling like you might pass out;
  • muscle twitches (tics);
  • trouble breathing;
  • changes in your vision;
  • chest pain;
  • skin color changes in your fingers or toes;
  • unexplained wounds;
  • cold feeling;
  • numbness;
  • paranoia;
  • hostility;
  • aggression;
  • new behavior problems;
  • hallucinations (seeing or hearing things that are not real).

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The most common adverse events include:

  • trouble sleeping;
  • nervousness;
  • weight loss;
  • dizziness;
  • loss of interest in sex;
  • restlessness;
  • chest pain;
  • headache;
  • fainting;
  • stomach ache;
  • decreased appetite;
  • dry mouth;
  • nausea;
  • constipation.

Serious side effects include:

  • severe skin rash;
  • aggressive behavior;
  • uncontrolled movements;
  • irregular heartbeat;
  • changes in vision;
  • difficulty swallowing;
  • seizures;
  • swelling of lips, face, or tongue;
  • uncontrollable behavior;
  • delusions;
  • severe weakness or numbness;
  • trouble breathing.


Take E401 pill by mouth with or without food as directed by your healthcare provider, commonly 1 to 3 times per day.

In children 6 years of age and older, the usual initial recommended dose of Adderall is 5 mg once or twice per day. The maximum recommended dose is 40 mg a day.

In children from 3 to 5 years of age, the usual initial recommended dose is 2.5 mg per day.

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Warnings & Precautions

E401 Pill

Do not use this drug if you have used an MAO inhibitor in the past 2 weeks, like –  linezolid, methylene blue injection, isocarboxazid, phenelzine, selegiline, rasagiline, or tranylcypromine.

Stimulants have caused heart attack, stroke, and sudden death in individuals with heart disease, hypertension, or a heart defect.

To make sure this CNS stimulant is safe for you, tell your healthcare professional if you or anyone in your family has ever had:

  • blood circulation problems in the hands or feet;
  • an abnormal brain wave test;
  • seizures or epilepsy;
  • Tourette’s syndrome;
  • suicidal thoughts or actions;
  • psychosis;
  • bipolar disorder;
  • mental illness;
  • depression.


There are several conditions your healthcare professional will need to be aware of before prescribing this drug for you, including any history of:

  • kidney disease;
  • hyperthyroidism;
  • liver disease;
  • glaucoma or any eye problems;
  • seizures;
  • any sudden, uncontrolled movements;
  • anxiety.

Do not stop taking this central nervous system stimulant suddenly.

This can cause extreme tiredness, severe depression, and other withdrawal symptoms.

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Drug Interactions

Both drugs may interact in a negative way with the following medications:

  • Zoloft (sertraline);
  • Cymbalta (duloxetine);
  • Wellbutrin XL (bupropion);
  • Lexapro (escitalopram);
  • Synthroid (levothyroxine);
  • Prozac (fluoxetine).


Consuming alcohol while taking these central nervous system stimulants is dangerous since these drugs mask the sedating effects of alcohol which commonly help prevent people from overdosing on alcohol.

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Is It Safe During Pregnancy or Breastfeeding?

E401 Pill

This central nervous system stimulant can pass into breast milk and may harm a nursing infant.

Do not breastfeed while you are using this drug.

Taking this central nervous system stimulant during pregnancy can lead to adverse effects for the developing fetus. Do not take this drug if you are pregnant.


Do not take this central nervous system stimulant while breastfeeding because the medication can pass through breast milk to a breastfeeding infant.

Also, this medication might be unsafe to take during pregnancy.

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E401 Pill vs Adderall – Differences

Both drugs contain amphetamine and dextroamphetamine and are prescribed for the treatment of:

  • the attention deficit hyperactivity disorder;
  • narcolepsy;
  • some forms of obesity;
  • depression, which is resistant to other medical treatments.

In conclusion, both drugs are central nervous system stimulants that work by increasing the availability of the neurotransmitters dopamine and norepinephrine in the central nervous system connections.

The difference is that Adderall is a brand name, whereas E401 pill is a generic name.

Note – when choosing between the two medications, it is important to discuss the pros and cons with your doctor to decide which one is right for you.

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