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Loryna vs Gianvi

Compare Loryna vs Gianvi:


Birth control pills (also called the “Pill” or oral contraceptive pills) are a form of female hormonal birth control method which is very efficient at preventing pregnancy.

An estimated 25% of women who use birth control today are on the pill.

It usually contains artificial versions of female hormones progesterone and estrogen, which females produce naturally in their ovaries.

When taken correctly, the pill is over 99 percent effective at preventing pregnancy.

Certain medications may make either type of pill less effective, such as:

  • certain antiseizure medications, like – topiramate and carbamazepine;
  • certain HIV medications, like – saquinavir and lopinavir;
  • rifampin (an antibiotic used to treat some types of bacterial infections).

Note – it can take several months for your period to go back to the cycle you had before you started taking oral contraceptive pills.

Here is a comparison between Loryna and Gianvi, two popular oral contraceptive pills:


It contains the same amounts of two female hormones: ethinyl estradiol and drospirenone.

Inactive ingredients:

  • titanium dioxide;
  • croscarmellose sodium;
  • talc;
  • ferric oxide;
  • pregelatinized starch;
  • lactose;
  • povidone K30;
  • magnesium stearate;
  • polyvinyl alcohol;
  • polysorbate 80;
  • polyethylene glycol.


It contains a combination of two medications:

  • ethinyl estradiol (0.02-mg) – it is a synthetic estrogen;
  • drospirenone (0.3-mg) – it is a synthetic progestin.

Inactive ingredients:

  • titanium dioxide;
  • corn starch;
  • talc;
  • ferric oxide;
  • povidone;
  • hypromellose;
  • magnesium stearate;
  • lactose.


Loryna is indicated for use by women to prevent pregnancy.

Also, it is approved to help treat moderate acne in women who are 14 years of age or older.

Gianvi is indicated for the prevention of pregnancy in females who choose to take an oral contraceptive.

It is also recommended for the treatment of moderate acne vulgaris in women at least 14 years of age.

Mechanism of Action

Loryna works by delivering hormones that block ovulation.

Gianvi works by inhibiting ovulation as well as producing changes in the cervical mucus and the endometrium.

Side Effects

Possible side effects of Loryna include:

  • tender breasts;
  • feeling more or less hungry;
  • a severe headache;
  • weight gain;
  • mood changes;
  • upset stomach or throwing up;
  • nipple discharge;
  • bloating;
  • breast soreness;
  • enlarged breasts;
  • a lump in the breast;
  • vaginal itching or discharge;
  • bulging eyes;
  • feeling tired or weak;
  • change in how contact lenses feel in the eyes;
  • loss of eyesight;
  • vaginal bleeding, which is very bad;
  • change in how much urine is passed;
  • low mood (depression);
  • lowered interest in sex.

Possible side effects of Gianvi include:

  • jaundice (yellowing of the skin or eyes);
  • problems with vision or balance;
  • sweating;
  • slurred speech;
  • swelling in your hands, ankles, or feet;
  • sudden severe headache;
  • pounding in your neck or ears;
  • sudden numbness or weakness;
  • blurred vision;
  • vomiting;
  • sudden vision loss;
  • breast tenderness;
  • stabbing chest pain;
  • nausea;
  • pain or warmth in one or both legs;
  • feeling tired or irritable;
  • coughing up blood;
  • mood changes;
  • feeling short of breath;
  • weight gain;
  • clay-colored stools;
  • decreased sex drive;
  • dark urine;
  • changes in your menstrual periods;
  • sleep problems;
  • pain spreading to your jaw or shoulder.


Take one tablet of Loryna by mouth at the same time every day.

Also, it is recommended to start taking the tablets either on the 1st Sunday after the onset of your menstrual period or on the 1st day of your menstrual period.

Take one pill of Gianvi every day, no more than 24 hours apart.

ALSO READ: Jardiance vs Farxiga

Warnings & Precautions

Do not take Loryna if you have a history of:

  • adrenal insufficiency (a disorder that occurs when the human body does not make enough of certain hormones);
  • certain types of headaches;
  • diabetes with eye, nerve, kidney, or blood vessel damage;
  • high blood pressure uncontrolled by medication;
  • kidney disease;
  • liver disease;
  • unexplained vaginal bleeding;
  • cancer of the lining of the cervix, uterus, or vagina;
  • breast cancer;
  • angina (chest pain);
  • blood clots in your lungs, legs, or eyes;
  • heart disease;
  • heart attack or stroke;
  • allergic reaction to any of its ingredients.

You should not take Gianvi if you have:

  • an increased risk of having blood clots due to a hereditary blood disorder or a heart problem;
  • an adrenal gland disorder;
  • unusual vaginal bleeding;
  • kidney disease;
  • if you take any hepatitis C medication;
  • uncontrolled high blood pressure;
  • if you smoke and are over 35 years old;
  • a history of heart attack;
  • liver disease;
  • coronary artery disease;
  • a history of jaundice caused by birth control pills;
  • circulation problems;
  • severe migraine headaches;
  • a history of hormone-related cancer.

Drug Interactions

Loryna may interact in a negative way with the following medications:

  • clonazepam;
  • Xanax (alprazolam);
  • levothyroxine;
  • Topamax (topiramate);
  • spironolactone (a drug that is used to treat fluid build-up due to liver scarring, heart failure, or kidney disease).

Gianvi may interact in a negative way with the following medications:

  • alprazolam;
  • topiramate (a broad-spectrum anticonvulsant drug);
  • clonazepam;
  • spironolactone;
  • metformin.


Alcohol won’t change the effectiveness of these birth control medications.

ALSO READ: Rexulti vs Latuda – Comparison

Is It Safe During Breastfeeding?

It is best to avoid using these birth control medications if you’re breastfeeding, as they can reduce the amount of your breast milk.

Loryna vs Gianvi – Differences

Loryna is a prescription birth control medication that prevents pregnancy by altering cervical mucus and the lining of the uterus and by stopping ovulation.

It contains two hormones – ethinyl estradiol and drospirenone, that belong to a family of drugs called hormonal contraceptives. Also, these pills are used to treat acne in women at least 14 years of age.

Gianvi is a prescription birth control medication that prevents pregnancy by altering cervical mucus and the lining of the uterus and by stopping ovulation.

It contains ethinyl estradiol and drospirenone, two hormones that belong to a family of drugs called hormonal contraceptives. In addition, this birth control medication is used to treat acne in women at least 14 years of age.

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5 Alternatives To The Birth Control Pill

For women who cannot use or do not wish to take the birth control pill, other options are available, such as:

#1 Vaginal Ring

A birth control vaginal ring is typically known by the brand name NuvaRing. It is usually inserted into your vagina once every 30 days to prevent pregnancy.

#2 Diaphragm

A contraceptive diaphragm is a circular dome made of soft silicone which is inserted into the vagina before sex.

#3 Intrauterine Devices

An intrauterine device is a tiny device that is put into your uterus to prevent pregnancy.

When inserted correctly, intrauterine devices are more than 99 percent effective.

#4 Male Condoms

Male condoms are worn on the penis.

They are the only type of contraception that can both protect against sexually transmitted infections and prevent pregnancy.

#5 Female Condom

A female condom is a pouch that you put inside the vagina to reduce the risk of pregnancy.